一 基本情况
赵灿灿，博士，河南驻马店人
二 教育工作经历
2022.06-至今 河南大学抗体药物开发技术国家地方联合工程实验室
2016.09-2021.06 南开大学 理学博士
2012.09-2016.07 河南大学 工学学士
三 主要研究方向
肿瘤免疫、巨噬细胞功能调控及机制研究
四 近五年研究成果
1. Zhao CC, Han QJ; Ying HY, Gu XX, Yang N, Li LY, Zhang QZ. TNFSF15 Facilitates Differentiation and Polarization of Macrophages toward M1 Phenotype to Inhibit Tumor Growth. Oncoimmunology, 2022, 11: 2032918. (Q1； IF: 7.723).
2. Wang ZH†, Zhao CC†, Zhang QZ, Wang CL, Zhang H, Ma DJ, Wang DW, Wen X, Li LY, Xi Z. Design, synthesis and systematic evaluation of all possible cyclic dinucleotides (CDNs) that activate human stimulator of interferon genes (STING) variants. Sci. China Chem. 63, 534– 545 (2020). (†Co-first author; Q1; IF:10.138）
3. Wang ZH†, Zhao CC†, Wang CL, Zhang H, Ma DJ, Zhang QZ, Wen X, Li LY, Xi Z. Synthesis and biological evaluation of all possible inosine-mixed cyclic dinucleotides that activate different hSTING variants. [J] .Bioorg Med Chem, 2020, 29: 115899. (†Co-first author；Q2; IF:3.461)
4. Ji RP, Shi QQ, Cao YX, Zhang JY, Zhao CC, Zhao HY, Sayyed Y, Fu L, Li LY. Inhibition of EGFR signal activation in breast cancer by an alternative splicing variant of the human rhomboid family-1 gene. (Journal of Biological Chemistry; Q2; IF: 5.486)
