一. 基本信息:
王佩玲,博士,中共党员,河南洛阳人
二.教育经历:
2010-2014 河南大学,中药学 理学学士
2014-2016 天津大学,细胞与分子药理学 理学硕士
2016-2020 天津大学,应用化学 工学博士
2017-2019 威斯康星大学麦迪逊分校,药学院,联合培养
三.主要研究方向
1. 有丝分裂激酶haspin的小分子抑制剂抗癌活性的研究
2. 蛋白激酶haspin在调控细胞周期进程中的功能和机制的研究
四.近五年研究成果
1. Wang P, Hua X, et al. Haspin inhibition delays cell cycle progression through interphase in cancer cells. J. Cell. Physiol. 2020; 235(5):4508-4519, JCR 2区, IF=5.546
2. Wang P, Li H, et al. Loss of haspin suppresses cancer cell proliferation by interfering with cell cycle progression at multiple stages. J. Cell. Sci. under review.
3. Sun Y, Wang P*, et al. BMAL1 and CLOCK proteins in regulating UVB‐induced apoptosis and DNA damage responses in human keratinocytes. J. Cell. Physiol. 2018; 233: 9563–9574, JCR 2区, IF=5.546 (co-first author)
4. Han L, Wang P, et al. Anti-melanoma activities of haspin inhibitor CHR-6494 deployed as a single agent or in a synergistic combination with MEK inhibitor. J. Cancer 2017; 8(15): 2933-2943, JCR 3区, IF=3.565
五.学术交流
1. 2019.03 Gave a research seminar to the Cell Division Group of the Carbone Cancer Center at the University of Wisconsin-Madison.
2. 2018.07 Presented a poster at the Gordon Research Seminar on Chromatin Structure and Function.
3. 2018.07 Attended the Gordon Research Conference.
4. 2015.11 & 2016.11 Presented posters at Doctoral Forum of SPST at Tianjin University.